We read almost 720 thousand points in your DNA and used Google DeepMind's AI to find the things that actually matter for your health. No jargon. Just clarity.
Out of nearly 720,000 data points, an AI built by Google DeepMind found 7 changes worth paying attention to. Explained like you're telling a friend.
One of the little machines that recycles Vitamin B12 inside your cells isn't working at full speed. B12 is huge for energy, brain function, and heart health.
This matters even more because you also have another vitamin-related finding (we'll get to it in the Vitamins section). It's like having two slow workers on the same assembly line — things still get done, but not as fast.
Ask your doctor about methylcobalamin (the "ready-to-use" form of B12) instead of regular B12. Also worth getting a homocysteine blood test to check if this is causing issues.
Deep inside your muscle cells, there's a small protein that helps muscles squeeze and relax. The AI gave it the highest concern score of all your results (99.7 out of 100).
The reassuring part? Scientists haven't linked this specific change to any known disease yet. But if you ever have unexplained muscle weakness or cramps, it's something your doctor should know about.
Your DNA has a change in the recipe for Type III collagen — the glue that holds your body together (skin, blood vessels, gut, everywhere).
Lots of people carry changes like this and feel perfectly fine. But if you've ever noticed that you bruise super easily, your skin is very soft or stretchy, or your joints bend more than other people's, this might be why.
The protein that acts as cement for your collagen has a change. Combined with the collagen finding above, two parts of your body's building system are slightly different.
This doesn't mean anything is broken — but it's a pattern your doctor might find interesting.
Your liver has tiny "delivery trucks" that carry medications and hormones inside to be processed. This doesn't matter day-to-day, but becomes useful if you're ever prescribed cholesterol medication, thyroid pills, or certain cancer treatments.
You have one changed copy of a gene that, if both copies were changed, could cause a rare type of seizures in babies (treatable with Vitamin B6). With just one copy, you are 100% healthy.
The only time this matters is if you're planning to have children and your partner happens to carry the same change.
Your brain cells have a cleaning system that removes worn-out proteins. Research found a small link between this change and a slightly higher chance of Parkinson's disease later in life.
Most people with this change never develop any problems at all. Staying active, sleeping well, and eating colorful foods are the best things you can do.
We checked the single most studied gene for Alzheimer's risk.
You got one E3 (the most common) and one E4. E4 is the strongest genetic predictor of late-onset Alzheimer's. Having one copy means your risk is roughly 3 times higher than average.
But here's the crucial context: most people with your combination never get Alzheimer's. Genes load the gun, but lifestyle pulls the trigger.
Exercise (the #1 proven brain protector) • Quality sleep (7-9 hours) • Social connection • Learning new things • Mediterranean-style eating • Managing blood pressure and cholesterol
This is probably the most actionable finding in your entire report.
Your body turns folic acid into its usable form about 70% slower than most people. You have two copies of this change, so both sides are running slow.
And remember: your B12 recycling is also slower. So you've got two parts of the same system running at reduced speed. The good news? There's a really simple fix.
1. Take methylfolate instead of regular folic acid — pre-activated form
2. Take methylcobalamin instead of regular B12
3. Ask your doctor for a homocysteine blood test
4. Eat your greens: spinach, lentils, avocado, broccoli
You have two copies of the most studied "weight gene." It makes you feel hungrier and less satisfied after eating. People with your version tend to weigh about 3-4 kg more than average.
But exercise cuts this effect almost in half. Your genes suggest a tendency — your habits decide the outcome.
Regular movement (the #1 countermeasure) • Protein and fiber at each meal • Paying attention to portions
Your body stops making the enzyme that digests milk sugar in adulthood. This is actually the original human default — about 65% of adults worldwide have this.
If dairy gives you bloating, now you know why. Hard cheese, yogurt, and butter are usually fine — bacteria have already eaten the problematic sugar.
Lactase pills before dairy • Lactose-free milk • Oat/almond/soy alternatives • Hard cheese and yogurt are usually fine
Your brain keeps dopamine active longer than most people's. Scientists call this the "Thinker" type.
The upside: Sharper focus, better memory, great performance on mental tasks. The flip side: More sensitivity to stress, anxiety, and caffeine. Think of it as a powerful engine that sometimes redlines.
Manage stress actively (walks, meditation, nature) • Go easy on caffeine • Build in recovery time after intense periods
Your DNA makes more "alarm" signals that trigger inflammation, and less "calm down" signals. Like a fire alarm that's too sensitive and a sprinkler system that's too slow.
What you eat and how you live has a massive impact on inflammation — probably more than your genes do.
Omega-3 foods (salmon, walnuts, flaxseed) • Colorful fruits and vegetables • Regular exercise • Good sleep • Less processed food and sugar
Your DNA affects how fast or slow you break down certain medications. This could be really useful for your doctor.
Your body's drug-processing machinery runs at about half speed for certain medications:
Blood thinners (clopidogrel) — might not work as well. Good alternatives exist.
Acid reflux pills (omeprazole, pantoprazole) — might need a different dose.
Some antidepressants (citalopram, escitalopram) — might need a lower starting dose.
If you're ever prescribed these drugs, just mention "I'm a CYP2C19 intermediate metabolizer" to your doctor or pharmacist. They'll know exactly what to do.
Everything boiled down into three buckets.
Google DeepMind's AI predicted the shapes of your affected proteins.
| Protein | What it does | AI confidence | Explore |
|---|---|---|---|
| APOE | Carries fats around your brain | 75.5% | Open 3D view → |
| COMT | Cleans up dopamine in your brain | 93.9% | Open 3D view → |
| MTHFR | Activates folic acid (B vitamin) | 88.6% | Open 3D view → |
98 DNA changes flagged by at least two AI tools as potentially important.
| # | ID | Gene | Change | SIFT | PolyPhen | Type |
|---|---|---|---|---|---|---|
| 1 | rs1983864 | LOXL4 | D/A | harmful | damaging | TG |
| 2 | rs193922176 | COL3A1 | G/A | harmful | damaging | GC |
| 3 | rs11568563 | SLCO1A2 | E/D | harmful | damaging | TG |
| 4 | rs372660425 | ALDH7A1 | N/S | harmful | damaging | TC |
| 5 | rs2228354 | MYL5 | F/S | harmful | damaging | TC |
| 6 | rs1801394 | MTRR | I/M | harmful | damaging | AG |
| 7 | rs80114247 | TMEM175 | M/T | harmful | damaging | TC |
| 8 | rs117737960 | OR6J1 | L/P | harmful | damaging | AG |
| 9 | rs1131603 | TCN2 | L/S | harmful | damaging | TC |
| 10 | rs41267807 | LPA | Y/C | harmful | damaging | TC |
| 11 | rs3754334 | EPHA2 | I/M | harmful | damaging | AG |
| 12 | rs35574803 | CMTM6 | T/A | harmful | damaging | TC |
| 13 | rs2076742 | ATP10A | W/C | harmful | damaging | CG |
| 14 | rs5361 | SELE | S/R | harmful | damaging | TG |
| 15 | rs41310927 | ASPM | S/G | harmful | damaging | TC |
| 16 | rs2307492 | FMO2 | F/S | harmful | damaging | TC |
| 17 | rs2640738 | EXPH5 | R/G | harmful | damaging | TC |
| 18 | rs2075773 | ANGEL1 | F/C | harmful | damaging | AC |
| 19 | rs36024412 | CRYBG2 | S/F | harmful | damaging | TG |
| 20 | rs17585974 | KANSL1 | K/T | harmful | damaging | TG |
| + 78 more variants in the full CSV export | ||||||
719,991 markers sent to Ensembl VEP. 2,932 change a protein.
Evolution analysis (SIFT) + 3D protein impact (PolyPhen-2).
98 changes checked via AlphaMissense. 7 "likely important."
Key variants cross-referenced with ClinVar and PharmGKB.
Protein shapes from AlphaFold database for visual exploration.
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